Small non coding RNAS deriving from tRNAs
Project manager: Laurence MARÉCHAL-DROUARD
Beyond their key role in translation, tRNAs play other important functions. Among them, small non-coding RNAs deriving from tRNA cleavage called tRFs (for tRNA Fragments) play major roles in various biological processes such as inhibition of translation, RNA degradation or regulation of gene expression via the silencing pathway. In the laboratory, our work aims to decipher the biogenesis and the function of plant tRFs.